"DRESSed" to kill: Fatal case report of drug rash with eosinophilia and systemic symptoms

doi:N/A

eISSN: None / ISSN: None

Netharland Journal of Critical Care

2012, Volume 16, Issue 6 : 216-219

Article

"DRESSed" to kill: Fatal case report of drug rash with eosinophilia and systemic symptoms

Kouwenberg I.C.

Koot R.

van de Horst J.

van Leeuwen H.J.

Department of Internal Medicine, Rijnstate Hospital, Arnhem, Netherlands

Department of Dermatology, Rijnstate Hospital, Arnhem, Netherlands

Department of Pathology, Rijnstate Hospital, Arnhem, Netherlands

Abstract

Multiorgan dysfunction syndrome (MODS) is a frequently encountered complication in patients who are admitted to the Intensive Care Unit with severe sepsis. Infrequently the same clinical syndrome can be caused by another pathophysiologic mechanism. We present a patient with possible Drug Rash, Eosinophilia and Systemic Symptoms (DRESS). This rare syndrome is caused by an allergic reaction to drugs. Treatment consists of discontinuation of the drug and supportive treatment. Early recognition of DRESS is vital to enable initiation of treatment at an early stage. Copyright © 2012, Nederlandse Vereniging voor Intensive Care. All Rights Reserved.

Keywords

DRESS

Drug rash

Eosinophilia

Fever

Skin rash

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