Netharland Journal of Critical Care
2014,
Volume 18,
Issue 4
: 12-15
Article
A fatal course of brain abscesses attributed to antibiotic treatment
1
Department of Critical Care, University of Groningen, University Medical Center, Groningen, Netherlands
2
Isala Klinieken Zwolle, Netherlands
Abstract
We present a case of a drug reaction with eosinophilia and systemic symptoms (DRESS) in a patient with brain abscesses. The adverse drug event presents with high fever, generalized rash, hypereosinophilia and organ dysfunction. The mainstay of treatment is cessation of the culprit drug, but in our case continuation of antibiotics was essential for the treatment of brain abscesses and alternative antibiotics were hardly, if at all, available.
Keywords
Antibiotics
DRESS
Drug eruption
Eosinophilia
Rash
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