Direct oral anticoagulants and critical care: A review of literature and current opinion

doi:N/A

eISSN: None / ISSN: None

Netharland Journal of Critical Care

2018, Volume 26, Issue 5 : 174-179

Review

Direct oral anticoagulants and critical care: A review of literature and current opinion

Lefevre E.R.

Wondergem M.J.

Ten Tusscher B.L.

Department of Internal Medicine, VU Medical Center, Amsterdam, Netherlands

Department of Haematology, VU Medical Center, Amsterdam, Netherlands

Department of Intensive Care, VU Medical Center, Amsterdam, Netherlands

Abstract

Since 2008, when the first direct oral anticoagulants (DOACs) were introduced in the Netherlands, there has been a steep rise in the number of patients using these new anticoagulants. Consequently, in critical care we will encounter these patients more frequently. Knowledge of the specialised management strategies, especially of DOAC-related bleeding, is essential. In this article we will review the complications of the use of DOACs and strategies to antagonise their effect in case of major haemorrhage or acute emergency interventions. © 2018, Netherlands Society of Intensive Care. All rights reserved.

Keywords

Critical care

Direct oral anticoagulants

DOACs

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