Netharland Journal of Critical Care
2013,
Volume 17,
Issue 1
: 25-29
Review
Drug induced lung injury - A case of fatal bleomycin interstitial pneumonitis
van der Sar-van der Brugge S.
,
van Ravenswaay Claasen H.
,
Abstract
Bleomycin is an antineoplastic agent that is known for its potential for fatal lung toxicity. Cell injury occurs through the formation of free radicals. Timely detection of bleomycin-induced pneumonitis (BIP) can be difficult and it is vital to keep a low index of suspicion in patients receiving bleomycin. We describe a patient with Hodgkin's lymphoma who died of bleomycin-induced lung injury in our intensive care unit. We discuss treatment options and review the literature.
Keywords
Bleomycin
Drug induced lung injury
Intensive care unit
Interstitial pneumonitis
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